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【Press Release】Toei Shinyaku Files Patent for King Agaricus KA21 for Improving Male Menopausal Symptoms such as ED and Hair Loss

【Press Release】Toei Shinyaku Files Patent for King Agaricus KA21 for Improving Male Menopausal Symptoms such as ED and Hair Loss

Posted on July 09 2024, By: MotoiAkitomo

【Press Release】Toei Shinyaku Files Patent for King Agaricus KA21 for Improving Male Menopausal Symptoms such as ED and Hair Loss

Expected Applications in Hair Growth, Menopausal Disorders, and ED Recovery Supplements for Men.

【Press Release】

English:https://en.atpress.com/news/401642

日本語:https://www.atpress.ne.jp/news/401642

中文:https://zh.atpress.com/news/401642

 

Toei Shinyaku Co., Ltd. (Headquarters:  Mitaka, Tokyo; CEO: Akitomo Motoi) conducted a joint study with Shigakkan  University’s Faculty of Health Sciences on our outdoor-cultivated Agaricus blazei/brasiliensis/subrufescens  KA21 strain (hereinafter referred to as King Agaricus KA21). The study confirmed the  improvement effects of King Agaricus KA21 intake on male menopausal symptoms such as  ED and hair loss. Based on these findings, we are pleased to report that we  have filed a patent for "Compositions for Improving Male Menopausal  Symptoms such as Hair Loss and ED, and Pharmaceuticals and Food Products  Containing These."

Overview

Patent Application Number: 2024-109541

Submission Date: July 8, 2024

Inventors: Hirobumi Tada, Akitomo Motoi

Patent Applicants: Toei Shinyaku Co., Ltd.,  Shigakkan University

 

Title of the Invention:

"Compositions for Improving Male  Menopausal Symptoms such as ED and Hair loss, and Pharmaceuticals and Food  Products Containing These."

 

Technical Field:

This invention relates to compositions for  improving male menopausal symptoms such as ED and hair loss, and  pharmaceuticals and food products containing these.

 

Study Data

24 men aged 50 to 70 were given 900mg of  outdoor-cultivated Agaricus KA21 daily for two months, and the indicators  related to male menopausal symptoms were compared before and after intake.  Significant improvements were observed in AMS (Aging Males Symptoms) scores,  indicators for assessing male menopausal symptoms including mental,  psychological, and physical aspects, EHS (Erection Hardness) scores for  evaluating ED, SHIM (Sexual Health Inventory for Men) scores for male sexual  health assessment, and hair loss conditions.

*P < 0.05, ***P < 0.001

 

About Male Menopausal Symptoms

Testosterone, a male hormone, plays a  crucial role in maintaining male physical and mental functions. However, the  amount of testosterone gradually decreases with age. External factors such as  lifestyle and stress also impact testosterone levels. Decreased testosterone is  closely related to conditions such as sarcopenia, which involves muscle loss  and muscle weakness, and also affects the causes and prevention of various  diseases, including angina, arteriosclerosis, obesity, metabolic syndrome, and  dementia. These conditions associated with decreased testosterone are known as  Late Onset Hypogonadism (LOH) syndrome. Reports indicate that about 10% of  middle-aged men in employment suffer from male menopausal symptoms, with a  notable prevalence starting from the late 40s, making LOH a significant social  and economic concern.

 

LOH manifests in a variety of symptoms  including general fatigue, decreased libido, lack of motivation, ED, difficulty  concentrating, insomnia, irritability, shoulder stiffness, urination problems,  a sense of heaviness in the head, and fewer morning erections. Additionally,  age-related testosterone decline increases the risk of several health issues  such as depression, sexual dysfunction, cognitive decline, cardiovascular  diseases, increased visceral fat, insulin resistance, decreased HDL  cholesterol, and elevated total cholesterol and LDL cholesterol.